17/30 How to Set up a Medical Lab - Presence Of Interferences

Welcome to Needle.Tube, Your Personal Supply Assistant. Today, we'll briefly discuss: Presence of interferences.

The presence of interferences in samples can significantly impact the accuracy and reliability of lab test results. Common interferences include hemolysis, lipemia, and icterus, which can alter the optical or chemical properties of the sample.

Hemolysis, often caused by improper blood draw techniques, releases intracellular components that can falsely elevate or lower test results. Lipemia, resulting from high fat content in the blood, can cloud the sample and interfere with spectrophotometric assays.

Icterus, caused by elevated bilirubin levels, can cause a yellow tint in the sample, affecting colorimetric tests. Medications and supplements taken by the patient can also interfere with certain assays, leading to inaccurate readings.

Recognizing these interferences early allows for corrective actions, such as requesting a new sample or using alternative testing methods. Understanding and managing sample interferences are crucial for ensuring that test results are accurate, reliable, and reflective of the patient’s true health status.

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