Additives in Blood Collection Tubes for Phlebotomy

Summary

• Understanding the common additives used in blood collection tubes is crucial for accurate Test Results.
• There are various types of additives used in blood collection tubes for different tests in phlebotomy.
• The additives help preserve the integrity of the blood sample and ensure accurate Test Results.

Additives in Blood Collection Tubes for Phlebotomy

When it comes to phlebotomy, accurate Test Results are crucial for diagnosing and treating patients. One way to ensure the accuracy of Test Results is by using blood collection tubes with specific additives. These additives help preserve the integrity of the blood sample and ensure that the tests are done correctly. In this article, we will explore the most common additives used in blood collection tubes for different types of tests in phlebotomy.

Types of Additives

There are various types of additives used in blood collection tubes, each serving a specific purpose. Some of the most common additives used in blood collection tubes include:

1. Anticoagulants
2. Antiglycolytic agents
3. Preservatives

Anticoagulants

Anticoagulants are additives used in blood collection tubes to prevent blood from clotting. Clotting can alter Test Results and make them inaccurate. Some common anticoagulants used in blood collection tubes include:

1. EDTA (Ethylenediaminetetraacetic acid): EDTA is a chelating agent that binds to calcium ions in the blood, preventing clotting.
2. Heparin: Heparin is a natural Anticoagulant that works by inhibiting the action of thrombin in the blood, preventing clot formation.

Antiglycolytic Agents

Antiglycolytic agents are additives used in blood collection tubes to prevent the breakdown of glucose in the blood sample. Glucose breakdown can affect Test Results, especially in tests that require glucose measurement. Some common antiglycolytic agents used in blood collection tubes include:

1. Sodium Fluoride: Sodium Fluoride inhibits the action of glycolytic enzymes in the blood, preventing glucose breakdown.
2. Oxalate: Oxalate also inhibits glycolytic enzymes and is often used in combination with other additives like EDTA.

Preservatives

Preservatives are additives used in blood collection tubes to prevent the degradation of certain components in the blood sample. These additives help maintain the integrity of the sample and ensure accurate Test Results. Some common preservatives used in blood collection tubes include:

1. Acid citrate dextrose (ACD): ACD is a preservative that prevents the degradation of red blood cells in the blood sample.
2. Citrate: Citrate is often used in coagulation tests to prevent the activation of clotting factors in the blood sample.

Conclusion

Understanding the common additives used in blood collection tubes is essential for phlebotomists to ensure accurate Test Results. By using the right blood collection tubes with the appropriate additives, Healthcare Providers can trust the validity of the Test Results and make informed decisions about patient care.

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