What is the volume range for small tubes, and which tests benefit from their use?

Small tubes, often referred to as microcollection tubes or microtainers, are designed to collect and handle smaller volumes of blood. These tubes are particularly useful in situations where only a limited amount of blood can be obtained, such as through capillary puncture (fingerstick or heelstick). The volume range for small tubes can vary, but they typically hold anywhere from 0.5 to 1.5 milliliters of blood. The specific volume capacity may depend on the manufacturer and the intended use of the tube.

Tests that benefit from the use of small tubes include:

Complete Blood Count (CBC):

Small tubes are suitable for CBCs, which include measurements of red blood cells, white blood cells, and platelets.


Basic Chemistry Panels:

Certain basic chemistry tests, including glucose, electrolytes, and liver function tests, can be performed using the smaller volumes of blood collected in microtainers.


Hemoglobin A1c (HbA1c):
Testing for HbA1c levels, which assesses long-term glucose control in diabetes management.


Blood Gas Analysis:
Small tubes are used for blood gas tests, including measurements of pH, oxygen, and carbon dioxide levels.


Point-of-Care Testing:
Rapid point-of-care tests, such as glucose monitoring and cardiac marker tests, can benefit from the use of small tubes.


Pediatric Testing:
Microtainers are often used for blood collection in pediatric patients, where obtaining larger volumes of blood may be challenging.


Coagulation Tests:
Basic coagulation tests like prothrombin time (PT) and activated partial thromboplastin time (APTT) can be performed using small volumes of blood.


Thyroid Function Tests:
Testing for thyroid hormones, including thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3).


Cardiac Markers:
Certain cardiac markers, such as troponin, may be measured using small tubes.


C-Reactive Protein (CRP):
Measurement of CRP levels, an indicator of inflammation.

Blood Typing:
ABO and Rh blood typing can be performed using small tubes.

Hematological Studies:
Various hematological studies, such as reticulocyte count and hemoglobin electrophoresis, can benefit from the use of small tubes.


The benefit of small tubes lies in their ability to collect smaller blood volumes, making them suitable for situations where venous blood collection is challenging or when only limited blood is needed for testing. As with any blood collection procedure, it's essential to follow the guidelines provided by the laboratory or healthcare provider for proper blood collection procedures using small tubes.

a-rack-full-of-blood-collection-tubes

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