What tests are typically performed using a dark blue top tube?

A dark blue top tube is not a standard tube color commonly used in routine blood collection. However, there are specialized situations where a dark blue top tube may be used for specific tests, especially in toxicology, trace metal analysis, and nutritional studies. The dark blue top tube is designed to contain a buffered sodium citrate additive, and it helps preserve the stability of certain analytes.

Dark Blue Top Tube:

Color: Dark blue.
Additive: Buffered sodium citrate.
Purpose: Preserves the stability of certain analytes for specialized tests.


Tests Associated with a Dark Blue Top Tube:
Trace Metal Analysis:
Dark blue top tubes may be used for the analysis of trace metals, such as lead, arsenic, and cadmium.
Toxicology Studies:
Some toxicology tests, particularly those requiring stabilization of certain analytes, may be performed using dark blue top tubes.
Nutritional Studies:
In specific nutritional studies, the dark blue top tube may be used to preserve the stability of certain nutrients or elements.
Specialized Chemistry Tests:
Certain specialized chemistry assays that benefit from the stability provided by buffered sodium citrate may use dark blue top tubes.


It's important to note that the use of dark blue top tubes is not common in routine blood collection, and their use is often specific to certain laboratories and tests. Additionally, the availability of dark blue top tubes may vary, and healthcare providers will specify the appropriate tube type based on the tests ordered.

As with any blood collection procedure, it's essential to follow the guidelines provided by the laboratory or healthcare provider for proper tube selection and collection techniques. If dark blue top tubes are required for specific tests, healthcare professionals should be aware of the specific handling and processing instructions to ensure accurate and reliable results.

a gloved hand holding four purple top blood collection tubes with blood specimen


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When is a yellow top tube used, and which tests does it support?

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When should a gray top tube be used, and what tests are commonly associated with it?